Prostate-Specific Antigen (PSA) Total Test
Prostate-Specific Antigen (PSA) Total Test is a laboratory test you can order directly. The Prostate-Specific Antigen (PSA) Total Test measures the amount of PSA, a protein made by the prostate gland, in your blood. It is often used to screen for prostate cancer, but it can also be ordered to monitor benign prostate conditions or to follow up after prostate cancer treatment.
- Sample type
- blood
- Category
- Cancer Screening
- Turnaround
- 1-3 business days
- Price
- $49
- Referral
- Not required
The Prostate-Specific Antigen (PSA) Total Test measures the amount of PSA, a protein made by the prostate gland, in your blood. It is often used to screen for prostate cancer, but it can also be ordered to monitor benign prostate conditions or to follow up after prostate cancer treatment.
What it measures
- Total PSA — The overall amount of PSA in your blood, measured in nanograms per milliliter (ng/mL).
- Free PSA — The portion of PSA that is not bound to other proteins; sometimes measured to help clarify risk when total PSA is mildly elevated.
- PSA ratio (free/total) — A calculation that compares free PSA to total PSA; a lower ratio may suggest a higher chance of prostate cancer.
- PSA velocity — How fast your PSA level changes over time, based on multiple tests; a rapid rise can be a concern.
- Age-specific PSA — A reference range adjusted for your age, since PSA naturally tends to rise as men get older.
Who it is for
A healthcare provider typically orders a PSA test for men who are considering prostate cancer screening, usually starting around age 50 or earlier if there is a family history. It may also be ordered to monitor known prostate conditions or treatment response.
Preparation
No fasting or special preparation is required for a PSA test. However, tell your provider if you have had a recent prostate exam, urinary infection, or ejaculation within 48 hours, as these can temporarily raise PSA levels.
Results and what they mean
Results are reported as a number in nanograms per milliliter (ng/mL). Your clinician will interpret the result along with your age, symptoms, and medical history; a single abnormal value does not diagnose cancer. This is general information, not medical advice; discuss your results with a qualified healthcare professional.
How to order this test
- Choose the test and place a confidential order online.
- Select a certified collection site and pick a time that suits you.
- Have your specimen collected — most draws take only a few minutes.
- Review results in a secure portal, typically within 1–3 days.
Preparation, hours, and pricing vary by site; confirm details directly with the lab before your visit.
Availability by state
Direct-access online ordering for the prostate-specific antigen (psa) total test is available in most states. It is currently unavailable in 6 states:
Everywhere else you can order confidentially and collect your sample at a certified site. Browse by state →
Frequently asked questions
What is a normal PSA level?
There is no single normal value. Many providers consider 4.0 ng/mL or lower as typical, but normal ranges vary with age and other factors. Your clinician will interpret your result in context.
Can I have a high PSA without cancer?
Yes. Benign prostate enlargement, prostatitis (prostate inflammation), recent ejaculation, or a urinary infection can raise PSA. A high result often leads to further testing.
How often should I get a PSA test?
Screening frequency depends on your age, risk factors, and prior results. Talk with your healthcare provider about what schedule is right for you.
Does the test require fasting?
No fasting is needed. You can eat and drink normally before the blood draw.