Hepatitis Immunity Detection & Vaccine Testing

Hepatitis Immunity Detection & Vaccine Testing can be requested without a referral, and this overview covers what to expect. Hepatitis immunity detection and vaccine testing is a blood test that checks whether you are protected against hepatitis A and hepatitis B, either from past infection or from vaccination. It is often ordered before travel, before starting certain jobs or school programs, or to confirm that a vaccine series worked.

Sample type
blood
Category
Sexual Health
Turnaround
1-3 business days
Price
$59
Referral
Not required

Hepatitis immunity detection and vaccine testing is a blood test that checks whether you are protected against hepatitis A and hepatitis B, either from past infection or from vaccination. It is often ordered before travel, before starting certain jobs or school programs, or to confirm that a vaccine series worked.

What it measures

  • Hepatitis A IgG antibody — Shows past infection or protection after hepatitis A vaccination.
  • Hepatitis B surface antibody (anti-HBs) — Shows immune protection, usually from vaccination.
  • Hepatitis B surface antigen (HBsAg) — A marker that can indicate current hepatitis B infection.
  • Hepatitis B core antibody (anti-HBc) — Helps distinguish past or current infection from vaccination alone.
  • Hepatitis C antibody — Sometimes added to screen for hepatitis C exposure.

Who it is for

Clinicians order this test for people who need proof of immunity, such as travelers, healthcare workers, students, or anyone starting a vaccine series. It may also be used after vaccination to confirm that protection developed.

Preparation

No fasting or special preparation is usually required. Tell your clinician about any vaccines you have received and when, since timing can affect the results.

Results and what they mean

Results are reported as positive, negative, or sometimes equivocal for each marker, with reference ranges from the lab. A clinician interprets these together with your vaccine history and symptoms; this is general information, not medical advice.

How to order this test

  1. Choose the test and place a confidential order online.
  2. Select a certified collection site and pick a time that suits you.
  3. Have your specimen collected — most draws take only a few minutes.
  4. Review results in a secure portal, typically within 1–3 days.

Preparation, hours, and pricing vary by site; confirm details directly with the lab before your visit.

Availability by state

Direct-access online ordering for the hepatitis immunity detection & vaccine testing is available in most states. It is currently unavailable in 6 states:

Everywhere else you can order confidentially and collect your sample at a certified site. Browse by state →

Frequently asked questions

Do I need to fast for this test?

No. Fasting is not required for hepatitis immunity or vaccine testing.

Can this test tell if I am protected from hepatitis B?

A positive hepatitis B surface antibody usually means you are protected, but your clinician will interpret it with your history.

How long after vaccination should I get tested?

Ask your clinician. Testing too soon after a vaccine series may give unclear results.

Is this test the same as a hepatitis screening test?

Not always. Immunity testing focuses on protection, while screening looks for current or past infection.

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