Genital Herpes (HSV-2) Blood Test
Genital Herpes (HSV-2) Blood Test can be requested without a referral, and this overview covers what to expect. The genital herpes (HSV-2) blood test checks for antibodies your immune system makes against herpes simplex virus type 2, the virus most often linked to genital herpes. It is usually ordered when someone has genital symptoms, when a partner has herpes, or as part of routine sexual health screening. Antibodies can take weeks to appear, so timing matters.
- Sample type
- blood
- Category
- Sexual Health
- Turnaround
- 1-3 business days
- Price
- $45
- Referral
- Not required
The genital herpes (HSV-2) blood test checks for antibodies your immune system makes against herpes simplex virus type 2, the virus most often linked to genital herpes. It is usually ordered when someone has genital symptoms, when a partner has herpes, or as part of routine sexual health screening. Antibodies can take weeks to appear, so timing matters.
What it measures
- HSV-2 IgG antibodies — Proteins made by your immune system after HSV-2 infection; their presence suggests past exposure.
- HSV-1 IgG antibodies — Often tested at the same time, since HSV-1 can also cause genital symptoms and may affect interpretation.
- IgM antibodies — Not routinely recommended because IgM results are unreliable for herpes and can be misleading.
- Index value — A number reported with the result; low-positive values may need a repeat or confirmatory test.
Who it is for
A clinician may order this test if you have genital sores or tingling, if a sexual partner has genital herpes, or as part of a sexual health check. It is not a routine test for everyone and is usually based on symptoms or risk.
Preparation
No fasting or special preparation is needed. Tell your clinician about any current genital symptoms and any antiviral medicines you take, since timing and treatment can affect results.
Results and what they mean
Results are usually reported as negative, positive, or equivocal (uncertain), often with an index value. A positive result means antibodies were found, but it does not show when you were infected or whether you have symptoms. A clinician interprets results alongside your history and symptoms. This is general information, not medical advice.
How to order this test
- Choose the test and place a confidential order online.
- Select a certified collection site and pick a time that suits you.
- Have your specimen collected — most draws take only a few minutes.
- Review results in a secure portal, typically within 1–3 days.
Preparation, hours, and pricing vary by site; confirm details directly with the lab before your visit.
Availability by state
Direct-access online ordering for the genital herpes (hsv-2) blood test is available in most states. It is currently unavailable in 6 states:
Everywhere else you can order confidentially and collect your sample at a certified site. Browse by state →
Frequently asked questions
Can this test tell me when I got herpes?
No. It shows whether antibodies are present, not when infection happened. A recently negative test followed by a positive one can suggest a recent infection, but timing is estimated by a clinician.
What does an equivocal result mean?
It means the result is unclear. Your clinician may repeat the test later or order a different confirmatory test.
Do I need to fast?
No. Fasting is not required for this blood test.
If I test positive but have no symptoms, what does that mean?
You may have been exposed to HSV-2 without noticeable symptoms. A clinician can explain what this means for you and your partners.