Hepatitis B Core Antibody Test
Below is a plain-language overview of the hepatitis b core antibody test. The hepatitis B core antibody test is a blood test that looks for antibodies your immune system makes against the core protein of the hepatitis B virus (HBV). It is ordered to find out whether you have ever been infected with HBV, either recently or in the past, and it is often used together with other hepatitis B tests to clarify your status.
- Sample type
- blood
- Category
- Sexual Health
- Turnaround
- 1-3 business days
- Price
- $24
- Referral
- Not required
The hepatitis B core antibody test is a blood test that looks for antibodies your immune system makes against the core protein of the hepatitis B virus (HBV). It is ordered to find out whether you have ever been infected with HBV, either recently or in the past, and it is often used together with other hepatitis B tests to clarify your status.
What it measures
- Hepatitis B core antibody (anti-HBc), total — Detects both IgM and IgG antibodies; a positive result usually means past or current infection.
- IgM anti-HBc — A marker that tends to appear during a recent or active infection.
- IgG anti-HBc — A marker that tends to appear later and can persist for life after infection.
- Hepatitis B surface antigen (HBsAg) — Often checked at the same time to see if the virus is currently present.
- Hepatitis B surface antibody (anti-HBs) — Often checked to see if you are protected, such as from vaccination.
Who it is for
A clinician may order this test if you have symptoms of hepatitis, have been exposed to HBV, have abnormal liver tests, or are being screened because of risk factors or pregnancy. It is also used to check whether a past infection has occurred before starting certain treatments.
Preparation
No fasting or special preparation is usually required. Tell your clinician about any medications or conditions, and follow any instructions you are given about timing.
Results and what they mean
Results are reported as positive or negative, sometimes with a numeric value, and are interpreted alongside other hepatitis B tests. A positive core antibody result does not by itself show whether the infection is current or past, so a clinician reviews the full panel and your history. This is general information, not medical advice; discuss your results with a qualified clinician.
How to order this test
- Choose the test and place a confidential order online.
- Select a certified collection site and pick a time that suits you.
- Have your specimen collected — most draws take only a few minutes.
- Review results in a secure portal, typically within 1–3 days.
Preparation, hours, and pricing vary by site; confirm details directly with the lab before your visit.
Availability by state
Direct-access online ordering for the hepatitis b core antibody test is available in most states. It is currently unavailable in 6 states:
Everywhere else you can order confidentially and collect your sample at a certified site. Browse by state →
Frequently asked questions
Does a positive result mean I have hepatitis B now?
Not necessarily. A positive core antibody can reflect a past infection that has cleared, a current infection, or sometimes a false result. Other tests help tell these apart.
Can the test tell if I was vaccinated?
No. The core antibody test is not used to check vaccine protection. A surface antibody test is used for that purpose.
How is the sample collected?
A small blood sample is drawn from a vein in your arm, usually in a clinic or lab.
How long until I get results?
Results are typically available within 1 to 3 business days, though timing can vary by lab.