LabInformationLab tests, explained

Cortisol AM & PM Test in Massachusetts

This page explains the cortisol am & pm test, what it measures, and how to arrange it. The Cortisol AM & PM Test measures cortisol levels in your blood at two different times of day. Cortisol is a hormone made by the adrenal glands that helps regulate stress response, blood sugar, and metabolism. Doctors order this test to check for conditions like Cushing's syndrome or Addison's disease, which affect cortisol production. Across Massachusetts, part of New England, the cortisol am & pm test can be ordered directly and collected at a certified site — no referral required.

Sample type
blood
Category
Hormone
Turnaround
1-3 business days
Price
$129
Referral
Not required

The Cortisol AM & PM Test measures cortisol levels in your blood at two different times of day. Cortisol is a hormone made by the adrenal glands that helps regulate stress response, blood sugar, and metabolism. Doctors order this test to check for conditions like Cushing's syndrome or Addison's disease, which affect cortisol production.

What it measures

  • Cortisol (morning) — The level of cortisol in your blood drawn in the morning, when it is usually highest.
  • Cortisol (evening) — The level of cortisol in your blood drawn in the evening, when it is usually lower.
  • Diurnal variation — The difference between morning and evening cortisol levels, which helps show if your daily rhythm is normal.

Who it is for

This test is typically ordered by an endocrinologist or primary care doctor when you have symptoms of a hormone imbalance, such as unexplained weight gain, fatigue, or high blood pressure.

Preparation

No special preparation is usually needed, but you may be asked to avoid eating, drinking caffeine, or exercising for a few hours before each blood draw. Your doctor will give you specific timing instructions for the morning and evening samples.

Results and what they mean

Results are reported as two cortisol values with reference ranges for the time of day. Your clinician will interpret these numbers along with your symptoms and other tests. This information is not medical advice; only a healthcare professional can diagnose or treat any condition.

Requesting the Cortisol AM & PM Test in Massachusetts

Order online, choose a certified collection site in Massachusetts, and review results through a secure portal. No referral is required, and orders are processed confidentially. Access across New England is tightly woven, so confirming a site ahead of time is worthwhile.

Frequently asked questions

Why do I need two blood draws?

Cortisol levels naturally rise and fall throughout the day. Testing both morning and evening helps show whether your daily pattern is normal.

Does this test require fasting?

Fasting is not always required, but your doctor may ask you to avoid food, caffeine, or exercise before the draws. Follow your specific instructions.

What can affect my cortisol results?

Stress, sleep, medications, pregnancy, and recent illness can all affect cortisol levels. Tell your doctor about any of these factors.

How long until I get my results?

Results are typically available within 1 to 3 business days. Your doctor's office will contact you about the findings.

Cortisol AM & PM Test by city in Massachusetts

All testing in Massachusetts →   Full Cortisol AM & PM Test guide →