Protein and Creatinine Urine Test
This page explains the protein and creatinine urine test, what it measures, and how to arrange it. The protein and creatinine urine test measures two substances in a urine sample: protein and creatinine. It is often ordered to check kidney function, screen for kidney damage, or monitor conditions like diabetes and high blood pressure that can affect the kidneys.
- Sample type
- urine
- Category
- Kidney
- Turnaround
- 1-3 business days
- Price
- $49
- Referral
- Not required
The protein and creatinine urine test measures two substances in a urine sample: protein and creatinine. It is often ordered to check kidney function, screen for kidney damage, or monitor conditions like diabetes and high blood pressure that can affect the kidneys.
What it measures
- Protein — A general marker of protein in urine; normally very low.
- Creatinine — A waste product from muscle; used to adjust for urine concentration.
- Protein-to-creatinine ratio — Calculated from the two measurements to estimate daily protein loss.
- Albumin — A specific protein; sometimes measured separately as albumin-to-creatinine ratio.
Who it is for
A healthcare provider may order this test if you have diabetes, high blood pressure, or symptoms suggesting kidney problems, or to monitor kidney health over time.
Preparation
Usually no special preparation is needed. You may be asked to collect a urine sample at a specific time, such as first thing in the morning, or to do a 24-hour collection; follow your provider's instructions.
Results and what they mean
Results are reported as amounts of protein and creatinine, often as a ratio. Your clinician interprets the numbers along with your health history; higher ratios may suggest kidney stress. This is general information, not medical advice.
How to order this test
- Choose the test and place a confidential order online.
- Select a certified collection site and pick a time that suits you.
- Have your specimen collected — most draws take only a few minutes.
- Review results in a secure portal, typically within 1–3 days.
Preparation, hours, and pricing vary by site; confirm details directly with the lab before your visit.
Availability by state
Direct-access online ordering for the protein and creatinine urine test is available in most states. It is currently unavailable in 6 states:
Everywhere else you can order confidentially and collect your sample at a certified site. Browse by state →
Frequently asked questions
Do I need to fast for this test?
No, fasting is not typically required. You can eat and drink normally unless your provider says otherwise.
Can I collect the sample at home?
Yes, many providers allow you to collect a urine sample at home and bring it to the lab. They will give you a container and instructions.
What does a high protein level mean?
It may indicate that your kidneys are filtering more protein than usual. Only a clinician can determine what your specific result means for you.
How long does it take to get results?
Results are usually available within 1 to 3 business days.