Oxycodone/Oxymorphone and Metabolite Screen
This page explains the oxycodone/oxymorphone and metabolite screen, what it measures, and how to arrange it. This test detects oxycodone, oxymorphone, and their breakdown products in a blood sample. It is ordered to check for recent use, confirm a prescribed medication is present, or investigate suspected overdose. Blood testing shows current levels rather than past use.
- Sample type
- blood
- Category
- Drug & Urine Screening
- Turnaround
- 1-3 business days
- Price
- $158
- Referral
- Not required
This test detects oxycodone, oxymorphone, and their breakdown products in a blood sample. It is ordered to check for recent use, confirm a prescribed medication is present, or investigate suspected overdose. Blood testing shows current levels rather than past use.
What it measures
- Oxycodone — The main prescription pain medication being tested for.
- Oxymorphone — A stronger metabolite (breakdown product) of oxycodone; also available as its own medication.
- Noroxycodone — Another metabolite of oxycodone, often measured to confirm the body processed the drug.
- Noroxymorphone — A metabolite of oxymorphone, useful for distinguishing sources.
Who it is for
Healthcare providers order this test in emergency rooms, pain management clinics, or during monitoring of prescribed opioid therapy. It may also be used in workplace or legal settings where recent use is relevant.
Preparation
No fasting or special preparation is needed. Tell the collector about any medications you take, including oxycodone or oxymorphone, because they can affect results.
Results and what they mean
Results are reported as detected or not detected, sometimes with a numeric level. A clinician interprets them alongside your history and other findings. This information is not medical advice; only your provider can explain what your results mean.
How to order this test
- Choose the test and place a confidential order online.
- Select a certified collection site and pick a time that suits you.
- Have your specimen collected — most draws take only a few minutes.
- Review results in a secure portal, typically within 1–3 days.
Preparation, hours, and pricing vary by site; confirm details directly with the lab before your visit.
Availability by state
Direct-access online ordering for the oxycodone/oxymorphone and metabolite screen is available in most states. It is currently unavailable in 6 states:
Everywhere else you can order confidentially and collect your sample at a certified site. Browse by state →
Frequently asked questions
How long after taking oxycodone can this blood test detect it?
Blood levels peak within a few hours and usually fall below detection within about 12 to 24 hours, though this varies by dose, metabolism, and individual factors.
Can this test tell if I took oxycodone versus oxymorphone?
Yes. The pattern of parent drug and metabolites can help a clinician see which substance was taken, but interpretation requires expertise.
Will my prescription cause a positive result?
Yes, if you take prescribed oxycodone or oxymorphone, the test is expected to be positive. Always inform the testing staff of your prescriptions.
Is this test confidential?
Yes. Results are protected health information and are shared only with those you authorize or as required by law.