Mono Test (Mononucleosis)
Mono Test (Mononucleosis) can be requested without a referral, and this overview covers what to expect. A mono test checks for infectious mononucleosis, a viral illness often called 'mono.' It is usually ordered when someone has a sore throat, swollen lymph nodes, and lasting tiredness that could be mono rather than a common throat infection.
- Sample type
- blood
- Category
- General Wellness
- Turnaround
- 1-3 business days
- Price
- $49
- Referral
- Not required
A mono test checks for infectious mononucleosis, a viral illness often called 'mono.' It is usually ordered when someone has a sore throat, swollen lymph nodes, and lasting tiredness that could be mono rather than a common throat infection.
What it measures
- Heterophile antibodies — Substances the immune system makes during mono; a rapid test looks for these.
- EBV viral capsid antigen (VCA) IgM — An antibody that tends to appear early in an Epstein-Barr virus infection.
- EBV VCA IgG — An antibody that usually appears later and can stay positive for life.
- EBV nuclear antigen (EBNA) — An antibody that typically shows up weeks to months after infection.
- Complete blood count (CBC) — A count of blood cells; certain white blood cells can look unusual during mono.
Who it is for
A clinician such as a primary care provider, urgent care provider, or pediatrician typically orders this test. It is most often used for teens and young adults with symptoms that suggest mono.
Preparation
No fasting or special preparation is needed. Tell the clinician about any medications or recent illnesses before the blood draw.
Results and what they mean
Results are reported as positive, negative, or sometimes unclear, along with antibody levels and blood cell counts. A clinician interprets these together with symptoms and history. This is general information, not medical advice; discuss your results with a qualified clinician.
How to order this test
- Choose the test and place a confidential order online.
- Select a certified collection site and pick a time that suits you.
- Have your specimen collected — most draws take only a few minutes.
- Review results in a secure portal, typically within 1–3 days.
Preparation, hours, and pricing vary by site; confirm details directly with the lab before your visit.
Availability by state
Direct-access online ordering for the mono test (mononucleosis) is available in most states. It is currently unavailable in 6 states:
Everywhere else you can order confidentially and collect your sample at a certified site. Browse by state →
Frequently asked questions
How is the mono test done?
It uses a blood sample, usually drawn from a vein in your arm. Some clinics first use a rapid finger-stick or in-office test.
How long until I get results?
Typical turnaround is 1 to 3 business days, though in-office rapid tests may give a result the same visit.
Can mono be detected right away?
Not always. Antibodies can take time to appear, so a test early in the illness may be negative even if you have mono.
Do I need to fast?
No. Fasting is not required for a mono test.