Lupus Panel
Lupus Panel is a laboratory test you can order directly. A lupus panel is a group of blood tests used to help evaluate for systemic lupus erythematosus (SLE), an autoimmune condition. It is ordered when symptoms such as joint pain, rashes, or unexplained fatigue suggest possible lupus, or to monitor known disease activity.
- Sample type
- blood
- Category
- General Wellness
- Turnaround
- 1-3 business days
- Price
- $249
- Referral
- Not required
A lupus panel is a group of blood tests used to help evaluate for systemic lupus erythematosus (SLE), an autoimmune condition. It is ordered when symptoms such as joint pain, rashes, or unexplained fatigue suggest possible lupus, or to monitor known disease activity.
What it measures
- Antinuclear antibodies (ANA) — A common screening test; a positive result can occur in lupus and other conditions.
- Anti-double-stranded DNA (anti-dsDNA) — An antibody more specific to lupus; levels may track disease activity.
- Anti-Smith (anti-Sm) antibody — Another antibody that can support a lupus diagnosis.
- Complement proteins (C3, C4) — Proteins that can be low when lupus is active.
- Complete blood count (CBC) — Checks for low blood counts, which can occur in lupus.
Who it is for
A primary care clinician, rheumatologist, or other specialist typically orders this panel when lupus is suspected or to follow disease activity.
Preparation
No fasting is usually required. Tell your clinician about any medications or supplements you take, as some can affect results.
Results and what they mean
Results are reported as individual values with reference ranges. A clinician interprets them alongside your symptoms and history; no single result confirms or rules out lupus. This is general information, not medical advice.
How to order this test
- Choose the test and place a confidential order online.
- Select a certified collection site and pick a time that suits you.
- Have your specimen collected — most draws take only a few minutes.
- Review results in a secure portal, typically within 1–3 days.
Preparation, hours, and pricing vary by site; confirm details directly with the lab before your visit.
Availability by state
Direct-access online ordering for the lupus panel is available in most states. It is currently unavailable in 6 states:
Everywhere else you can order confidentially and collect your sample at a certified site. Browse by state →
Frequently asked questions
Do I need to fast for this test?
No, fasting is not typically needed for a lupus panel.
What does a positive ANA mean?
A positive ANA can occur in lupus but also in other conditions and in some healthy people. It is not a diagnosis by itself.
Can this test tell me if I definitely have lupus?
No. Lupus is diagnosed by combining symptoms, physical exam, and multiple test results. A clinician makes the final assessment.
How long do results take?
Most results are available within 1–3 business days, though some specialized tests may take longer.