Cocaine Metabolite Screen and Confirmation
Below is a plain-language overview of the cocaine metabolite screen and confirmation. A cocaine metabolite screen checks a blood sample for substances the body makes after cocaine use. If the screen is positive, a confirmation test is usually run to verify the finding. It is ordered when recent cocaine exposure needs to be detected or ruled out.
- Sample type
- blood
- Category
- Drug & Urine Screening
- Turnaround
- 1-3 business days
- Price
- $45
- Referral
- Not required
A cocaine metabolite screen checks a blood sample for substances the body makes after cocaine use. If the screen is positive, a confirmation test is usually run to verify the finding. It is ordered when recent cocaine exposure needs to be detected or ruled out.
What it measures
- Benzoylecgonine — Main metabolite detected in blood; its presence suggests recent cocaine use.
- Cocaine — The parent drug itself; detectable only briefly after use.
- Ecgonine methyl ester — Another breakdown product that can support a positive finding.
- Cocaethylene — Formed when cocaine and alcohol are used together; may indicate combined use.
- Confirmation result — A second, more specific method used to verify a screen-positive sample.
Who it is for
The test is typically ordered by emergency clinicians, workplace health providers, or other clinicians when recent cocaine exposure is suspected or must be ruled out.
Preparation
No fasting or special preparation is usually required. Tell the clinician about any medicines you take, since some can affect test results.
Results and what they mean
Results are reported as negative or positive, with confirmation results noted separately. A positive result does not by itself prove impairment or how much was used. Only a clinician can interpret results in context; this is general information, not medical advice.
How to order this test
- Choose the test and place a confidential order online.
- Select a certified collection site and pick a time that suits you.
- Have your specimen collected — most draws take only a few minutes.
- Review results in a secure portal, typically within 1–3 days.
Preparation, hours, and pricing vary by site; confirm details directly with the lab before your visit.
Availability by state
Direct-access online ordering for the cocaine metabolite screen and confirmation is available in most states. It is currently unavailable in 6 states:
Everywhere else you can order confidentially and collect your sample at a certified site. Browse by state →
Frequently asked questions
How long after cocaine use can this test detect it?
Cocaine itself clears quickly, while metabolites may remain detectable for a somewhat longer but still limited time. Timing varies by person and amount used.
If my screen is positive, does that mean I used cocaine?
A positive screen is usually confirmed with a second method before being considered reliable. Some substances can cause false positives, so a clinician reviews the full picture.
Can I prepare for this test?
No fasting or special preparation is needed. Sharing your medication list and recent substance use with your clinician helps with accurate interpretation.
Will the results be kept private?
Results are handled as confidential medical information and shared only as permitted by law or with your consent. Ask your testing site how your results will be used.