C-Reactive Protein Test, High Sensitivity
Below is a plain-language overview of the c-reactive protein test, high sensitivity. The high-sensitivity C-reactive protein (hs-CRP) test measures a protein in the blood that rises with inflammation. It is often ordered to estimate heart disease risk, since low-level inflammation can contribute to cardiovascular problems. Unlike standard CRP tests, this version detects very small increases.
- Sample type
- blood
- Category
- Cardiac
- Turnaround
- 1-3 business days
- Price
- $158
- Referral
- Not required
The high-sensitivity C-reactive protein (hs-CRP) test measures a protein in the blood that rises with inflammation. It is often ordered to estimate heart disease risk, since low-level inflammation can contribute to cardiovascular problems. Unlike standard CRP tests, this version detects very small increases.
What it measures
- High-sensitivity C-reactive protein (hs-CRP) — A protein made by the liver; higher levels suggest more inflammation in the body.
Who it is for
Clinicians may order this test for adults with no symptoms but with other heart risk factors, or to help assess cardiovascular risk when used with cholesterol and other tests.
Preparation
No fasting is required. Timing can matter if you are sick or had a recent injury, so tell your clinician about any recent illness or inflammation.
Results and what they mean
Results are reported as a number in milligrams per liter (mg/L). Your clinician interprets this value along with your medical history, cholesterol levels, and other risk factors. This is general information, not medical advice; only a qualified clinician can interpret your results.
How to order this test
- Choose the test and place a confidential order online.
- Select a certified collection site and pick a time that suits you.
- Have your specimen collected — most draws take only a few minutes.
- Review results in a secure portal, typically within 1–3 days.
Preparation, hours, and pricing vary by site; confirm details directly with the lab before your visit.
Availability by state
Direct-access online ordering for the c-reactive protein test, high sensitivity is available in most states. It is currently unavailable in 6 states:
Everywhere else you can order confidentially and collect your sample at a certified site. Browse by state →
Frequently asked questions
Do I need to fast for this test?
No, fasting is not needed for the hs-CRP test.
Can a high result mean I have heart disease?
Not necessarily. A high result only shows inflammation and may be due to infection, injury, or other causes. Your clinician will consider the full picture.
How often should I get this test?
There is no standard schedule. Your clinician will decide if and when repeat testing is useful for you.
What can affect my hs-CRP level?
Recent illness, injury, smoking, obesity, and some medications can raise levels. Tell your clinician about any recent health changes.