Arthritis & Inflammation Tests

Below is a plain-language overview of the arthritis & inflammation tests. Arthritis and inflammation tests are blood tests that look for signs of inflammation in the body. They help a clinician evaluate joint pain, swelling, or stiffness and monitor conditions such as rheumatoid arthritis or other inflammatory disorders.

Sample type
blood
Category
Inflammation
Turnaround
1-3 business days
Price
$198
Referral
Not required

Arthritis and inflammation tests are blood tests that look for signs of inflammation in the body. They help a clinician evaluate joint pain, swelling, or stiffness and monitor conditions such as rheumatoid arthritis or other inflammatory disorders.

What it measures

  • C-reactive protein (CRP) — A protein made by the liver that rises when inflammation is present.
  • Erythrocyte sedimentation rate (ESR) — Measures how quickly red blood cells settle; a faster rate can suggest inflammation.
  • Rheumatoid factor (RF) — An antibody that is often found in rheumatoid arthritis but can appear in other conditions.
  • Anti-CCP antibody — An antibody that is more specific for rheumatoid arthritis than RF.
  • Antinuclear antibodies (ANA) — Antibodies that can be present in autoimmune conditions such as lupus.
  • Uric acid — A waste product that can be elevated in gout, a type of inflammatory arthritis.

Who it is for

A primary care clinician, rheumatologist, or other specialist typically orders these tests when a person has ongoing joint pain, swelling, or other signs of inflammation.

Preparation

Most of these tests need no special preparation, though some labs may ask you to fast if other tests are done at the same time. Tell your clinician about all medicines and supplements you take, because some can affect the results.

Results and what they mean

Results are reported as numbers or as positive/negative for antibodies, and your clinician compares them with your symptoms and history. A single result rarely gives a full picture, so follow-up testing or repeat testing may be needed. This information is general and not medical advice; only a qualified clinician can interpret your results and decide what they mean for you.

How to order this test

  1. Choose the test and place a confidential order online.
  2. Select a certified collection site and pick a time that suits you.
  3. Have your specimen collected — most draws take only a few minutes.
  4. Review results in a secure portal, typically within 1–3 days.

Preparation, hours, and pricing vary by site; confirm details directly with the lab before your visit.

Availability by state

Direct-access online ordering for the arthritis & inflammation tests is available in most states. It is currently unavailable in 6 states:

Everywhere else you can order confidentially and collect your sample at a certified site. Browse by state →

Frequently asked questions

Do I need to fast for this test?

Usually not, but fasting may be required if other tests are ordered with it. Follow the instructions you are given.

How long until I get results?

Results are typically available in 1 to 3 business days, though some antibody tests may take longer.

Can these tests diagnose arthritis?

They can support a diagnosis, but no single blood test confirms arthritis. Your clinician uses results along with your symptoms, exam, and sometimes imaging.

What if my results are positive?

A positive result does not always mean disease. Your clinician will consider the full picture and may order more tests.

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