Alpha-Fetoprotein (AFP) Tumor Marker Test
Alpha-Fetoprotein (AFP) Tumor Marker Test is a laboratory test you can order directly. The alpha-fetoprotein (AFP) tumor marker test measures the level of AFP in your blood. AFP is a protein normally made by a developing fetus, but it can also be produced by certain cancers, so doctors order this test to help detect or monitor some tumors.
- Sample type
- blood
- Category
- Protein
- Turnaround
- 1-3 business days
- Price
- $44
- Referral
- Not required
The alpha-fetoprotein (AFP) tumor marker test measures the level of AFP in your blood. AFP is a protein normally made by a developing fetus, but it can also be produced by certain cancers, so doctors order this test to help detect or monitor some tumors.
What it measures
- Alpha-fetoprotein (AFP) — The main protein measured; high levels can be a sign of certain cancers or liver conditions.
- Total AFP — The overall amount of AFP in your blood, without separating different forms.
- AFP-L3% — Sometimes measured to see what portion of AFP is a specific subtype linked to liver cancer.
Who it is for
Doctors typically order this test for people with known or suspected liver cancer, testicular cancer, or ovarian cancer, and for those with chronic liver disease who are at higher risk.
Preparation
No special preparation is usually needed. You can eat and drink normally before the blood draw, and no fasting is required.
Results and what they mean
Results are reported as a number, often in nanograms per milliliter (ng/mL), along with a reference range from the lab. Your clinician interprets the result based on your medical history, symptoms, and other tests. This information is not medical advice; only your healthcare provider can explain what your results mean for you.
How to order this test
- Choose the test and place a confidential order online.
- Select a certified collection site and pick a time that suits you.
- Have your specimen collected — most draws take only a few minutes.
- Review results in a secure portal, typically within 1–3 days.
Preparation, hours, and pricing vary by site; confirm details directly with the lab before your visit.
Availability by state
Direct-access online ordering for the alpha-fetoprotein (afp) tumor marker test is available in most states. It is currently unavailable in 6 states:
Everywhere else you can order confidentially and collect your sample at a certified site. Browse by state →
Frequently asked questions
Is this test used to screen for cancer in everyone?
No. It is mainly used for people with a known or suspected tumor or those at higher risk due to liver disease. It is not a general screening test for all cancers.
Can a high AFP level mean I definitely have cancer?
No. AFP can be elevated in other conditions, such as liver inflammation or pregnancy. Your doctor will consider other tests to make a diagnosis.
How often should I have this test?
Your doctor will decide how often based on your situation. It may be repeated to monitor treatment or check for recurrence.
Does pregnancy affect AFP results?
Yes. AFP is naturally high during pregnancy, so the test is interpreted differently for pregnant women. Tell your doctor if you are pregnant.