LabInformationLab tests, explained

Estradiol Test, Ultrasensitive in Massachusetts

This page explains the estradiol test, ultrasensitive, what it measures, and how to arrange it. An estradiol test, ultrasensitive, measures very low levels of estradiol, a form of estrogen, in the blood. It is ordered when standard estradiol tests are not sensitive enough, often to monitor hormone therapy or evaluate certain hormone-related conditions. Across Massachusetts, part of New England, the estradiol test, ultrasensitive can be ordered directly and collected at a certified site — no referral required.

Sample type
blood
Category
Hormone
Turnaround
1-3 business days
Price
$198
Referral
Not required

An estradiol test, ultrasensitive, measures very low levels of estradiol, a form of estrogen, in the blood. It is ordered when standard estradiol tests are not sensitive enough, often to monitor hormone therapy or evaluate certain hormone-related conditions.

What it measures

  • Estradiol — The main estrogen measured; ultrasensitive methods detect very small amounts.
  • Total estradiol — The overall amount of estradiol in the blood sample.
  • Free estradiol (calculated) — The portion not bound to proteins, estimated from other results.
  • Sex hormone binding globulin (SHBG) — A protein that binds estradiol; sometimes measured to interpret free levels.
  • Testosterone (total) — Often checked alongside estradiol when hormone balance is evaluated.

Who it is for

A clinician may order this test for people receiving estrogen therapy, those with symptoms of hormone imbalance, or when monitoring certain treatments. It is also used in some fertility and gender-affirming care settings.

Preparation

No fasting is usually required. Tell your clinician about all medications, including estrogen products, as timing and dose can affect results.

Results and what they mean

Results are reported as a number with a reference range, which varies by age, sex, and lab method. A clinician interprets the result in the context of your symptoms, medications, and other tests. This is general information, not medical advice; discuss your results with a qualified healthcare professional.

Requesting the Estradiol Test, Ultrasensitive in Massachusetts

Order online, choose a certified collection site in Massachusetts, and review results through a secure portal. No referral is required, and orders are processed confidentially. Access across New England is tightly woven, so confirming a site ahead of time is worthwhile.

Frequently asked questions

Do I need to fast for this test?

No, fasting is not typically required. Follow any instructions from your clinician.

How soon will I get results?

Most results are available within 1 to 3 business days, though this can vary by lab.

Can my medications affect the result?

Yes. Estrogen products, some fertility drugs, and other hormones can change estradiol levels. Tell your clinician what you take.

Is this test the same as a regular estradiol test?

It uses a more sensitive method to detect very low levels, which a standard test may miss.

Estradiol Test, Ultrasensitive by city in Massachusetts

All testing in Massachusetts →   Full Estradiol Test, Ultrasensitive guide →